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Feng X, López Del Amo V, Mameli E, Lee M, Bishop AL, Perrimon N, Gantz VM.
Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes. Nature Communications May 20, 2021 doi: 10.1038/s41467-021-23239-0 PubMed PMID: 34017003 PubMed Central PMCID: PMC8137705 |
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Xuechun Feng, Lukas Kambic, Jared H.K. Nishimoto, Floyd A. Reed, Jai A. Denton, Jolene T. Sutton, and Valentino M. Gantz.
Evaluation of Gene Knockouts by CRISPR as Potential Targets for the Genetic Engineering of the Mosquito Culex quinquefasciatus. The CRISPR Journal. July 19, 2021 doi: doi.org/10.1089/crispr.2021.0028 |
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Li Z, Marcel N, Devkota S, Auradkar A, Hedrick SM, Gantz VM, Bier E.
CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion. Nature Communications May 11, 2021 doi: 10.1038/s41467-021-22927-1 PubMed PMID: 33976171 PubMed Central PMCID: PMC8113449 |
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Long KC, Alphey L, Annas GJ, Bloss CS, Campbell KJ, Champer J, Chen CH, Choudhary A, Church GM, Collins JP, Cooper KL, Delborne JA, Edwards OR, Emerson CI, Esvelt K, Evans SW, Friedman RM, Gantz VM, Gould F, Hartley S, Heitman E, Hemingway J, Kanuka H, Kuzma J, Lavery JV, Lee Y, Lorenzen M, Lunshof JE, Marshall JM, Messer PW, Montell C, Oye KA, Palmer MJ, Papathanos PA, Paradkar PN, Piaggio AJ, Rasgon JL, Rašić G, Rudenko L, Saah JR, Scott MJ, Sutton JT, Vorsino AE, Akbari OS.
Core commitments for field trials of gene drive organisms. Science. Dec 18, 2020 doi: 10.1126/science.abd1908 PubMed PMID: 33335055 |
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Adolfi A, Gantz VM, Jasinskiene N, Lee HF, Hwang K, Terradas G, Bulger EA, Ramaiah A, Bennett JB, Emerson JJ, Marshall JM, Bier E, James AA.
Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi. Nature Communications 2020 Nov 3 doi: 10.1038/s41467-020-19426-0 PubMed PMID: 33144570 PubMed Central PMCID: PMC7609566 |
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Xu XS, Bulger EA, Gantz VM, Klanseck C, Heimler SR, Auradkar A, Bennett JB, Miller LA, Leahy S, Juste SS, Buchman A, Akbari OS, Marshall JM, Bier E.
Active Genetic Neutralizing Elements for Halting or Deleting Gene Drives. Molecular Cell Oct 15, 2020 doi: 10.1016/j.molcel.2020.09.003 PubMed PMID: 32949493 |
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Nikolay P Kandul, Junru Liu, Anna Buchman, Valentino M Gantz, Ethan Bier, Omar S Akbari
Assessment of a split homing based gene drive for efficient knockout of multiple genes G3: GENES, GENOMES, GENETICS February 1, 2020 vol. 10 no. 2 827-837; doi: doi.org/10.1534/g3.119.400985 |
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Víctor López Del Amo, Brittany S. Leger, Kurt J. Cox, Shubhroz Gill, Alena L. Bishop, Garrett D. Scanlon, James A. Walker, Valentino M. Gantz, Amit Choudhary
Small-molecule control of super-Mendelian inheritance in gene drives Cell Reports, June 30th, 2020 PubMed PMID: 32610142 doi: doi.org/10.1016/j.celrep.2020.107841 BiorXiv, June 14th, 2019. doi: doi.org/10.1101/665620 |
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Víctor López Del Amo, Alena L. Bishop, Héctor M. Sánchez C., Jared B. Bennett, Xuechun Feng, John M. Marshall, Ethan Bier & Valentino M. Gantz
A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment Nature Communications, January 17th, 2020 PubMed PMID: 31953404 doi: doi.org/10.1038/s41467-019-13977-7 BiorXiv, June 28th, 2019. doi: doi.org/10.1101/684597 |
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Annabel Guichard , Tisha Haque , Marketta Bobik , Xiang-Ru S. Xu, Carissa Klanseck , Raja Babu Singh Kushwah, Mateus Berni, Bhagyashree Kaduskar, Valentino M. Gantz & Ethan Bier.
Efficient allelic-drive in Drosophila Nature Communications, April 9th, 2019. PubMed PMID: 30967548 doi: doi.org/10.1038/s41467-019-09694-w |
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Hannah A. Grunwald, Valentino M. Gantz, Gunnar Poplawski, Xiang-ru S. Xu, Ethan Bier, Kimberly L. Cooper
Super-Mendelian inheritance mediated by CRISPR/Cas9 in the female mouse germline. Nature, January 23rd, 2019. PubMed PMID: 30675057 doi: doi.org/10.1038/s41586-019-0875-2 BioRxiv, July 4th, 2018. doi: doi.org/10.1101/362558 |
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Valentino M. Gantz and Omar S. Akbari.
Gene editing technologies and applications for insects Current Opinion in Insect Science 2018, 28:xx–yy PubMed PMID: 30551769 doi: doi.org/10.1016/j.cois.2018.05.006 |
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Xiang-Ru S. Xu, Valentino M. Gantz, Natalia Siomava, Ethan Bier.
CRISPR/Cas9 and Active Genetics-based trans-species replacement of the endogenous Drosophila kni-L2 CRM reveals unexpected complexity. eLife 2017;6:e30281 PubMed PMID: 29274230 doi: 10.7554/eLife.30281 |
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Zach Adelman, Omar Akbari, John Bauer, Ethan Bier, Cinnamon Bloss, Sarah R Carter, Craig Callender, Adriana Costero-Saint Denis, Peter Cowhey, Brinda Dass, Jason Delborne, Mary Devereaux, Peter Ellsworth, Robert M Friedman, Valentino Gantz, Clark Gibson, Bruce A Hay, Mark Hoddle, Anthony A James, Stephanie James, Lyric Jorgenson, Michael Kalichman, John Marshall, William McGinnis, Jack Newman, Alan Pearson, Hector Quemada, Larisa Rudenko, Anthony Shelton, Joseph M Vinetz, Jennifer Weisman, Brenda Wong & Chris Wozniak.
Rules of the road for insect gene drive research and testing. Nature Biotechnology 2017, 35, 716–718 PubMed PMID: 28787415 doi:10.1038/nbt.3926 |
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Gantz VM, Bier E.
The dawn of active genetics. Bioessays. 2016 Jan; 38(1):50-63. Epub 2015 Dec 10. PubMed PMID: 26660392 doi: 10.1002/bies.201500102 |
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Gantz VM, Jasinskiene N, Tatarenkova O, Fazekas A, Macias VM, Bier E, James AA.
Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi. PNAS. 2015 Dec 8;112(49):E6736-43. Epub 2015 Nov 23. PubMed PMID: 26598698; PubMed Central PMCID: PMC4679060 doi: 10.1073/pnas.1521077112. |
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Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O'Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J.
BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science. 2015 Aug 28;349(6251):927-9. Epub 2015 Jul 30. PubMed PMID: 26229113 PubMed Central PMCID: PMC4692367 doi: 10.1126/science.aac7932. |
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Valentino M. Gantz & Ethan Bier
The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations Science, 24 Apr 2015, Vol. 348, Issue 6233,pp. 442-444. Epub 19 Mar 2015 PMID: 25908821 PMCID: PMC4687737 DOI: 10.1126/science.aaa5945 |
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